Tag: biotech

  • CrisprBits raises $3 million to scale CRISPR diagnostics, biofuel strain engineering

    CrisprBits raises $3 million to scale CRISPR diagnostics, biofuel strain engineering

    Team CrisprBits. CrisprBits, a Bengaluru biotech startup, has raised $3 million in a pre-Series A round to scale its CRISPR-based diagnostics and gene-editing platforms, lifting its valuation to $12 million.
    Team CrisprBits. Image source: company.

    CrisprBits, a Bengaluru biotech startup, has raised $3 million in a pre-Series A round to scale its CRISPR-based diagnostics and gene-editing platforms, lifting its valuation to $12 million. The company plans to use the money to commercialize its PathCrisp molecular diagnostics line and build an AI-augmented strain engineering platform for industrial biofuels.

    Listen to the episode


    The round was led by Spectrum Impact, the family office of Aarti Industries Ltd.’s Chairman and Managing Director Rajendra Gogri, with participation from existing backers including the Vijay Alreja Family Office (VJ Technologies Group) and new investors such as the promoter family of HBL Engineering Ltd. Earlier funding from the founders, VJ Technologies Group and C-CAMP is being deployed to expand manufacturing capacity across human health, food safety and animal health applications.

    CrisprBits’ investment is happening at a time when CRISPR moves from lab tool to commercial platform in diagnostics, gene therapies and industrial biotech, drawing sustained interest from strategics and financial investors worldwide. Global CRISPR technology revenues are projected to grow at around 11–16 percent annually this decade, with estimates putting the broader CRISPR market in the $5–23 billion range by 2030–2035 as applications in healthcare, agriculture and biomanufacturing scale up.

    “Our focus has always been on attracting patient capital that shares our goal to ‘rewrite biology and reimagine the planet,’ CrisprBits co-founder and CEO Vijay Chandru, said in a press release. “This round gives us the fuel to launch in India and immediately scale to global markets with high-quality, affordable solutions,” he said.

    CrisprBits’ PathCrisp platform targets rapid, point-of-need molecular diagnostics, promising sample-to-result times of under 2.5 hours with minimal infrastructure. The product line spans tests for typhoid, antimicrobial resistance, sickle cell disease, foodborne pathogens and on-farm animal disease surveillance, aimed at hospitals, food processors and livestock producers.

    Beyond diagnostics, the company’s EdiCrisp platform offers end-to-end gene-editing services using the indigenous enFnCas9 system from the Institute of Genomics and Integrative Biology, positioned as more precise than legacy SpCas9 systems.

    A third platform, CurieCrisp, combines patient-derived iPSC lines, CRISPR-corrected controls and AI analytics to support preclinical research and rare disease drug discovery, with an emphasis on improving access in the Global South.

    CRISPR stands for clustered regularly interspaced short palindromic repeats, referring to a pattern of repeated DNA sequences found in bacteria and archaea – a major group of single-celled microorganisms.

    CRISPR-Cas9 is a gene-editing technology that acts like molecular scissors, allowing scientists to cut and modify DNA at specific locations in the genome. The tool was adapted for genome editing in 2012 by researchers including Jennifer Doudna and Emmanuelle Charpentier, whose work on CRISPR-Cas9 earned them the 2020 Nobel Prize in Chemistry and set off a wave of applications in medicine, agriculture and basic research.

    Consultancy and market-research estimates suggest that CRISPR-related markets are entering a scale-up phase, particularly in health care. One global forecast pegs the CRISPR technology market at about $3.2 billion in 2025, rising to roughly $5.5 billion by 2030 at an annual growth rate of just over 11 percent, driven by demand for genetic disease therapies, functional genomics tools and next-generation diagnostics.

    Within diagnostics, CRISPR-based tests are expected to grow faster than the broader market as they move into point-of-care infectious disease testing and oncology. The CRISPR-based diagnostics segment alone is projected to climb from around $3.8 billion in 2025 to more than $15 billion by 2034, implying a CAGR of about 16–17 percent as new products win regulatory approvals and reimbursement.

    India has emerged as an early adopter of CRISPR diagnostics, starting with the FELUDA assay developed by CSIR-IGIB and Tata Group in 2020, which demonstrated the feasibility of low-cost CRISPR-based testing for infectious diseases.

    Last week, Union Minister Jitendra Singh launched ‘BIRSA 101’, India’s first indigenous CRISPR-based gene therapy for sickle cell disease, developed at CSIR-IGIB and transferred to the Serum Institute. The therapy aims to make advanced gene-editing cures affordable for Indian patients, particularly tribal populations, supporting the ambition for a Sickle Cell–free India by 2047.

    Domestic market forecasts indicate that India’s CRISPR gene detection and diagnostic segment could grow from around $50 million in the mid-2020s to more than $240 million by 2032, with biomedical diagnostics as the largest and fastest-growing application.

    Recent initiatives include new CRISPR laboratories in Bengaluru for gene editing and diagnostics, and a pipeline of rare-disease and oncology programmes exploring CRISPR-based interventions. Against this backdrop, CrisprBits — founded by BITS Pilani alumni and operating a 7,300-square-foot CRISPR R&D facility in Bengaluru — aims to extend India’s footprint from diagnostic kits to platforms spanning gene editing and sustainable industrial biotechnology.

    With the fresh capital, CrisprBits plans to ramp up manufacturing at its diagnostics facility and expand distribution into Africa and Latin America over the next six months. In parallel, it intends to build an AI-augmented strain engineering platform focused initially on biofuel production, targeting cost and sustainability gains for industrial partners in chemicals and energy.

  • India’s first S&T and innovation conclave, Eli Lilly’s $1 bln plan

    India’s first S&T and innovation conclave, Eli Lilly’s $1 bln plan

    Daily brief on deep tech and climate tech from India and around the world.

    India’s Science and Tech minister Dr. Jitendra Singh (centre) at the curtain raiser for the country’s first science, tech and innovation conclave.

    Minister Dr. Jitendra Singh launches Emerging Science, Technology & Innovation Conclave
    Union Minister Dr. Jitendra Singh launched a curtain-raiser for the Emerging Science, Technology & Innovation Conclave (ESTIC-2025), according to a ministry press release yesterday. The three-day conclave, to be held in Delhi starting Nov. 3, will focus on technologies including semiconductors, AI, quantum computing, biotech, space, and clean energy. It is designed to be a platform for young innovators, startups, and researchers to showcase their solutions and connect with industry leaders.

    Listen to the episode

    DPIIT and Thermo Fisher Scientific to support 500 biotech startups
    India’s Department for Promotion of Industry and Internal Trade (DPIIT) has partnered Thermo Fisher Scientific to launch the BioVerse Challenge, a national programme aimed at supporting 500 biotech startups in India over the next three years, according to a press release from the commerce ministry. The collaboration will provide mentorship, access to advanced R&D facilities, and investor connections. This initiative is a key step towards achieving India’s vision of building a $300 billion bioeconomy by 2030.

    Eli Lilly to invest over $1 billion in India manufacturing expansion
    US pharmaceutical company Eli Lilly will invest more than $1 billion to expand its manufacturing and supply capabilities in India, Reuters reports. The investment includes new contract manufacturing facilities and a new manufacturing and quality hub in Hyderabad. The company’s goal is to strengthen its global supply chain and leverage India’s skilled workforce to increase the availability of key medicines for conditions such as diabetes, obesity, and cancer.

    RoosterBio and Secretome Therapeutics complete large-scale production for clinical cell therapy
    RoosterBio and Secretome Therapeutics have successfully completed large-scale bioreactor production of STM-01, a cell therapy candidate for heart failure currently in clinical trials, the US companies said in a press release. This new process, which replaces a less efficient flask-based method, is designed to increase productivity and scalability, and will be transferred to Secretome’s contract manufacturer.

    California to create statewide strategy for quantum technology
    California has enacted a new law, Assembly Bill 940, to establish a statewide strategy for the quantum technology sector, Quantum Insider reports. Led by the Governor’s Office of Business and Economic Development (GO-Biz), the plan aims to attract investment, foster job growth, and coordinate public-private partnerships. The initiative, backed by $4 million in state funding for research, seeks to translate the state’s academic research into commercial applications, ensuring California’s global competitiveness in this transformative field.

    Firefly Aerospace acquires SciTec in $855 million deal
    Firefly Aerospace has acquired SciTec, a national security technology firm, for $855 million to enhance its space services, the two US companies said in a press release. SciTec’s defense software analytics and capabilities in missile warning, tracking, and intelligence will bolster Firefly’s offerings in the growing military-space sector. SciTec will operate as a unit of Firefly, which is now poised to strengthen its position as a major space technology provider, known for its small- to medium-lift launch vehicles, lunar landers, and orbital vehicles.

    Einride raises $100 million for autonomous freight deployments
    Einride, a startup in Sweden specializing in autonomous and electric freight technology, has secured $100 million in new funding, the company said in a press release. The capital will be used to accelerate the deployment of its self-driving trucks, advance its technology, and expand its customer base. The funding follows a year of significant growth for the company, including a doubling of its net sales and expansion into new markets.

  • India approves $12 billion R&D and I fund, Loopworm’s insect protein tech, Aureka’s sustainable diamonds get Peak XV sparkle, and more

    India approves $12 billion R&D and I fund, Loopworm’s insect protein tech, Aureka’s sustainable diamonds get Peak XV sparkle, and more

    Daily brief on deep tech and climate tech news from India and around the world

    Rajiv Ganth, founder and CEO, CIMware, is leading innovation that can help make data centre power use more efficient and therefore boost sustainability.

    Google signs landmark deal with Commonwealth Fusion Systems to commercialize fusion energy

    Google has entered its first commercial fusion energy agreement, committing to purchase 200 megawatts of clean power from Commonwealth Fusion Systems’ (CFS) inaugural ARC (affordable, robust and compact) plant in Virginia, expected to go online in the early 2030s.

    The partnership deepens Google’s investment in CFS, a Massachusetts-based MIT spinout, and includes an option to offtake power from future ARC facilities. The move signals growing confidence in fusion’s potential to deliver scalable, carbon-free electricity to meet surging energy demand from big tech data centres.

    Listen to the podcast

    Omnisent secures $3 million to pioneer acoustic AI for industrial intelligence

    Omnisent, a sound technologies and AI startup in Munich, Germany, has raised $3 million in a pre-seed round led by Atlantic Labs, Tech Funding News reports.

    The startup, founded in late 2024 by Robin Daiber, Ann-Kristin Balve, and Adrien Jathe, has developed a platform that uses proprietary ultra-low-power sonic sensors and a large acoustic AI model to convert industrial noise into real-time insights, targeting inefficiencies like compressed air leaks.

    The fresh funds will support R&D, team growth, and a commercial launch in Q4 2025, as Omnisent aims to expand into energy, defence, and smart cities.

    CIMware raises $2.3 million to tackle data center scalability with sustainable smart switch

    CIMware, a data centre infrastructure venture in Bengaluru, has raised $2.3 million in Pre-Series-A funding led by Transition VC, the company said in a press release. CIMware was founded in 2019 by Rajiv Ganth, a veteran in distributed systems and data centre engineering.

    Ganth, who has previously worked at companies including LSI and Dell EMC, leads CIMware’s push to address data centre scalability and efficiency with its patented Composable Infrastructure Module, a converged smart switch built in India. CIMware says its technology can reduce power consumption by up to 80 percent, offering a more sustainable alternative for AI-driven workloads, according to the release.

    Loopworm raises $3.25 million to commercialize silkworm-based protein platform

    Loopworm, a biomanufacturing startup in Bengaluru, has raised $3.25 million in a pre-Series-A round led by WaterBridge Ventures and Japan’s Enrission India Capital, Entrackr reports.

    Founded by IIT-Roorkee alumni Ankit Alok Bagaria and Abhi Gawri in 2019, Loopworm has developed a reactor-free system using silkworms to produce recombinant proteins for diagnostics and animal vaccines, promising faster, cheaper, and more sustainable production. Backed by investors including Omnivore, the company operates a 6,000-tonne-per-year insect processing facility and exports to Europe, South America, and ASEAN markets.

    Aukera raises $15 million led by Peak XV Partners to expand lab-grown diamond retail

    Aureka, a lab-grown diamond jewellery startup, has raised $15 million in growth capital led by Peak XV Partners, with participation from Fireside Ventures, Sparrow Capital, Prath Ventures, and Alteria Capital.

    The Bengaluru-based company will use the funds to expand its retail footprint, enhance product offerings, and strengthen its omnichannel presence. Founded two years ago by Lisa Mukhedkar and Kumar Saurabh, Aukera operates 13 stores nationwide and aims to lead India’s rapidly growing lab-grown diamond market amid rising demand for sustainable luxury.

    India’s Cabinet approves $12 billion R&D and innovation fund to boost private R&D in strategic sectors

    India’s Union Cabinet, chaired by Prime Minister Narendra Modi, has approved an R&D and Innovation (RDI) Scheme, establishing a Rs. 1 lakh crore ($12 billion) fund to catalyze private sector investment in research, development, and innovation across strategic and sunrise sectors.

    The scheme offers long-term, low or zero-interest financing to overcome funding barriers and promote technology adoption, self-reliance, and competitiveness, according to a press release yesterday.

    A two-tier funding structure will be managed by the Anusandhan National Research Foundation, with the Department of Science and Technology as the nodal agency. The RDI Scheme aims to finance transformative projects, support acquisition of critical technologies, and facilitate a Deep-Tech Fund of Funds, positioning India for global leadership in innovation as it targets developed nation status by 2047.


    In Conversation

    In-depth conversations with entrepreneurs, investors, industry leaders and other stakeholders building India’s deep tech and climate tech ecosystems.